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Associations between DNA Damage, DNA Base Excision Repair Gene Variability and Alzheimer’s Disease Risk

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Dysbiotic microbiota correlated with PD-like functional and pathological changes in both the gut and the brain, as seen in the association of above-mentioned bacterial families with intestinal epithelial barrier integrity (assessed by ZO-1 expression), inflammation (assessed by the number of CD3 + T-cells in the colon), α-syn accumulation in the colonic plexi and the number of DA neurons in the SN